Benzene derivatives or their salts, such as Quinasa Pi3 inhibitors; pharmacological synthesis containing these substances; and selected low-level PTEN new plasma for the treatment of cerebral hemocytes, breast cancer, prostate cancer, gastric cancer and multiple myeloma E, among other things.

摘要

p BENZMIDAZOLE DERIVATIVES OF FOAMULA 1 ARE DESCRIBED FOR THE MODULATION, NOTARILY OF THE INHIBITION, OF THE ACTIVITY OR FUNCTION OF THE PHOSPHINOSITIDE KINASE FAMILY 3 # 39; OH (LATER THEREIN THE KINASES P13),In the treatment of 1 or M amp, pi3ka, pi3kb, and / or pi3kb, and / or pi3kg; Aacute; selected diseases from the following diseases: autoimmune disorder and amp; oacute; gicos, inflammation, cardiovascular disease, neurodegenerative disease, allergy, asthma, pancreatitis, M amp failure; uacute; ltples amp; oacute; organ, Oacute; platelet n, C amp; Aacute; NCER, sperm fluidity, rejection of transplantation, rejection of transplantation, lung injury; eacute, uticas. / P