Phenylacetamide derivatives, quinase inhibitors for anaerobic lymphoma; pharmacological synthesis; pharmacological binding; and compounds (d) for the treatment of diffusive disorders such as lymphoma, osteoma, melanoma, breast cancer, renal cancer, prostate cancer, etc. (IVSITAL Application 3552-07).

摘要

The invention provides novel pyrimidine and pyridine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.