Couple B - gdb aptamers and their use in the treatment of diseases or Disorders mediated by B - NGF

摘要

The present Disclosure provides several aptamers that bind to the beta subunit of nerve growth factor, mentioned individually in this Invention as "aptamer beta NGF, and Methods for using such aptamers to treat beta NGF mediated diseases and disorders Beta NGF treatment, including Pain and pruritus and pruritic conditions.Include Pharmaceutical compositions and formulations comprising an aptamer beta NGF or one of its Salts are acceptable from the point of view of pharmaceutical acceptable Carrier and at least one from a Pharmaceutical Point of view.