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Composition for the Prevention, Treatment and Diagnosis of Chronic Obstructive Pulmonary Disease (COPD)
Composition for the Prevention, Treatment and Diagnosis of Chronic Obstructive Pulmonary Disease (COPD)
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机译:预防,治疗和诊断慢性阻塞性肺疾病(COPD)的组合物
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摘要
The present invention provides a pharmaceutical composition for preventing or treating chronic obstructive pulmonary disease (COPD) comprising cytokeratin 18 protein as an active ingredient. The present invention also provides a diagnostic composition and a diagnostic kit for diagnosing COPD comprising cytokeratin 18 protein. The present invention further provides a composition for screening a therapeutic agent for COPD, comprising one or more of cytokeratin 18 protein or autoantibodies to cytokeratin 18 obtained from patients with COPD and a method for screening a therapeutic agent for COPD using this composition. The present invention still further provides methods for diagnosing, preventing or treating COPD using cytokeratin 18 protein.
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