Substituted tetrahydrothienopyridines corresponding to formula (1) in which A1 through A3 and R1 through R12 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds and the use of such compounds in treatment or inhibition of conditions mediated by the KCNQ 2/3 K+ channel, e.g., pain.
展开▼
机译:对应于其中A1至A3和R1至R12具有定义含义的式(1)的四氢噻吩并吡啶类化合物,包含此类化合物的药物组合物,制备此类化合物的方法以及此类化合物在治疗或抑制由KCNQ 2介导的病症中的用途/ 3 K +通道,例如疼痛。
展开▼