METHOD FOR PRODUCING binding molecules specific to proteins associated with the disorder or an antibody or binding fragment thereof or at least one immunoglobulin chains LINKING aforementioned PROTEIN (VARIANTS) binding molecules, antibodies, CIRCUIT immunoglobulins or their binding fragments (VARIANTS) , POLYNUCLEOTIDE, VECTOR AND CELL-HOST, THEIR INCLUDING COMPOSITION

摘要

New specific binding molecules, in particular human antibodies, as well as fragments, derivatives and variants that recognize the neoepitopes of disease-related proteins, which originate from native endogenous proteins, but predominate in the patient’s body in altered form and / or outside their normal range, are envisaged. physiological condition. In addition, pharmaceutical compositions are described, including such binding molecules, antibodies and their facial expressions, and methods for detecting new binding molecules that may or may not be antibodies, as well as targets in the treatment of neurological disorders such as Alzheimer's disease.