MONOCLONAL HUMAN ANTIBODIES OBTAINED FROM HUMAN B-CELLS AND HAVING NEUTRALIZING ACTIVITY AGAINST THE VIRUS AIRFLOWER

摘要

The invention relates to human monoclonal antibodies obtained from human B cells present in the blood of patients recovered after infection with influenza A viruses, said antibodies having neutralizing activity against influenza A viruses. These monoclonal antibodies against influenza A virus according to the present invention have binding and neutralizing activity against at least one influenza A virus selected from the group consisting of subtypes H1, H2 and H5 of influenza A virus, and thus m, are useful for the prevention and treatment of diseases caused by the specified influenza A virus, as well as for the diagnosis of influenza A virus infection.