APPLICATION OF METMORPHINE IN COMBINATION WITH GLUCOKINASE ACTIVATOR AND COMPOSITIONS CONTAINING METMORPHIN AND GLUCOKINASE ACTIVATOR

摘要

The invention relates to the use of glucokinase activator in combination with metformin in medicine. Uses include treating type 2 diabetes, reducing glucose, improving insulin sensitivity, increasing glucose phosphorylation, and improving the therapeutic efficacy of metformin. In addition, the invention relates to pharmaceutical compositions containing the activator GK and metformin. The invention also relates to the salt formed by metformin and the GK activator.