USE OF BENZOTHIAZOLE DERIVATIVES IN THE MANUFACTURE OF MEDICAMENTS FOR TREATING DISEASES RELATED TO THE ADENOSINE RECEPTOR, SOME SUCH NOVEL BENZOTHIAZOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

摘要

The present invention relates to compounds of the general formula (I) and to their pharmaceutically acceptable salts for the treatment of diseases related to the adenosine A2 receptor, novel compounds of formula I-A per se,their manufacture, medicaments based on a compound in accordance with the invention and their production as well as the use of compounds of compounds of formula I in the control or prevention of illnesses based on the modulation of the adenosine system, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses hypoxia, ischaemia, seizure and substance abuse. Furthermore, compounds of the present invention may be useful as sedatives, muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardiaprotective agents.