Aza-bicycloalkyl ethers, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the prevention and treatment of psychotic and neurodegenerative disorders

摘要

The present invention relates to 1-aza-bicycloalkyl derivatives of formual I, wherein X is CH 2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.