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HYBRID STRIP FOR RAPID DETECTION OF MYCOBACTERIUM TUBERCULOSIS

机译:杂交条快速检测结核分枝杆菌

摘要

The present invention is a Hybrid Strip for Rapid Detection of Mycobacterium tuberculosis. The strip comprises a supporting body and thereon a sample pad a conjugate reagent pad a test membrane and an absorbent pad. The conjugate reagent pad is coated with specific receptor-gold complexes which interact with PCR products carried to this pad via capillary action and thereby forms complexes. The above complexes will keep migrating by capillary action on the test membrane where a test line an internal control line and a system control line are coated thereon. These 3 lines may individually capture the target component of the complexes and then generate color reactions. According to the result of the color reactions the existence of MTBC as well as the PCR inhibitors can be determined.
机译:本发明是用于快速检测结核分枝杆菌的杂种条。该条包括支撑体,其上具有样品垫,结合试剂垫,测试膜和吸收垫。偶联物试剂垫涂有特定的受体-金复合物,该复合物通过毛细管作用与运至该垫的PCR产物相互作用,从而形成复合物。上述络合物将通过毛细管作用而继续在测试膜上迁移,在该测试膜上涂覆有测试线,内部控制线和系统控制线。这3条线可以分别捕获复合物的目标组分,然后产生显色反应。根据显色反应的结果,可以确定MTBC以及PCR抑制剂的存在。

著录项

  • 公开/公告号IN2011DE03196A

    专利类型

  • 公开/公告日2013-01-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN3196/DEL/2011

  • 发明设计人 LIN YU HSUAN;CHOU GEORGE CHIN SHENG;

    申请日2011-11-11

  • 分类号

  • 国家 IN

  • 入库时间 2022-08-21 16:41:18

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