首页> 外国专利> pharmaceutical formulation in the form of a bilayer tablets comprising an inhibitor of hmg coa ru00c9ductase and irbu00c9sartan

pharmaceutical formulation in the form of a bilayer tablets comprising an inhibitor of hmg coa ru00c9ductase and irbu00c9sartan

机译:双层片剂形式的药物制剂,包含hmg coa r u00c9ductase和irb u00c9sartan抑制剂

摘要

the present invention relates to a pharmaceutical formulation in the form of tablets, bi layer consisting of a first layer containing the pharmaceutically acceptable salts of irbesartan and thereof, and a second layer containing a hmg coa reductase inhibitor and an additive f tto improve the dissolution rate and stability of irbesartan, an inhibitor of hmg coa reductase activity in order to increase the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of related compounds.in such a way as to be effectively used as a therapeutic agent is stable and superior in high blood pressure and cholesterol.
机译:本发明涉及片剂形式的药物制剂,该双层由包含厄贝沙坦及其药学上可接受的盐的第一层和包含hmg coa还原酶抑制剂和添加剂以提高溶出速率的第二层组成的双层组成hmg coa还原酶活性抑制剂厄贝沙坦的稳定性和稳定性,以便与常规复杂制剂相比提高药物的生物利用度并最大程度地减少相关化合物的产生。以有效用作治疗剂的方式稳定并且在高血压和胆固醇方面表现出色。

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