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IMPROVED LIPOSOMAL FORMULATIONS OF LIPOPHILIC COMPOUNDS.

机译:改进的脂族化合物的脂质体配方。

摘要

The present invention relates to the preparation of liposomes with enhanced loading capacity for pharmaceutically and/or diagnostically active agents and/or cosmetic agents which are substantially solubilized by the liposomal membranes, to liposome dispersions with enhanced stability with respect to release of the active agent and/or cosmetic agent from the liposomes obtainable by the process, and to pharmaceutical or cosmetic compositions comprising said stabilized liposome dispersions. The preparation may involve dehydration and rehydration steps of liposome dispersions which may be carried out by spray drying.
机译:本发明涉及脂质体的制备,所述脂质体对基本上被脂质体膜溶解的药学和/或诊断活性剂和/或美容剂的负载能力增强,涉及相对于活性剂释放和释放具有增强的稳定性的脂质体分散体。可通过该方法获得的脂质体中的/和/或美容剂,以及包含所述稳定的脂质体分散体的药物或美容组合物。该制备可涉及脂质体分散体的脱水和再水合步骤,其可通过喷雾干燥进行。

著录项

  • 公开/公告号MX2012013528A

    专利类型

  • 公开/公告日2013-04-03

    原文格式PDF

  • 申请/专利权人 MEDIGENE AG;

    申请/专利号MX20120013528

  • 发明设计人 HEINRICH HASS;URSULA FATTLER;

    申请日2011-05-20

  • 分类号A61K9/127;A61K9/16;A61K31/337;

  • 国家 MX

  • 入库时间 2022-08-21 16:40:49

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