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DEXAMETHASONE COMBINATION THERAPY.

机译:地塞米松联合疗法。

摘要

The present invention relates to a method of treating multiple myeloma in a subject comprising administering to the subject an amount of (1) a compound of formula (I), as described herein, and/or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, and an amount of (2) dexamethasone and/or a pharmaceutically acceptable salt, solvate, metabolite or racemate thereof, such that the subject is treated. In another aspect, provided herein is a method of treating multiple myeloma in a subject comprising administering to the subject an amount of (1) a compound of formula (I) and an amount of (2) dexamethasone, such that the subject is treated; pharmaceutical formulations comprising said combination for the treatment of multiple myelom; and compositions thereof.
机译:本发明涉及一种在受试者中治疗多发性骨髓瘤的方法,该方法包括向该受试者施用一定量的(1)如本文所述的式(I)的化合物和/或其立体异构体,互变异构体或其药学上可接受的盐。 ,和一定量的(2)地塞米松和/或其药学上可接受的盐,溶剂化物,代谢产物或外消旋物,以使受试者得到治疗。在另一方面,本文提供了一种在受试者中治疗多发性骨髓瘤的方法,其包括向所述受试者施用一定量的(1)式(I)的化合物和一定量的(2)地塞米松,从而治疗所述受试者;包含所述组合的用于治疗多发性骨髓瘤的药物制剂;及其组成。

著录项

  • 公开/公告号MX2013005271A

    专利类型

  • 公开/公告日2013-09-26

    原文格式PDF

  • 申请/专利权人 BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;

    申请/专利号MX20130005271

  • 发明设计人 QING YI;YUHUAN ZHENG;

    申请日2011-11-11

  • 分类号A61K31/5377;A61K31/573;A61P35;

  • 国家 MX

  • 入库时间 2022-08-21 16:40:40

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