Compound Pharmaceutical composition, use of a compound and Method for treating Disorders associated with serotonergic receptor 5-ht1a and 5-ht2a

摘要

Refers to piperazino compounds derived from alkyl phenyl 4 (3H) - quinazolinona of formula (i) wherein R1 is H or Ethyl, N is 2; R2 is 3 - trifluormetilfenil, 2-chlorophenyl, 2-methylphenyl dimetilfenil, 2,3 -, 2 - cianofenil, among others.Preferred compounds are: 3 - (2 - (4 - (3 - (trifluoromethyl) phenyl) piperazin-1-yl) ethyl) quinazolin-4 (3H) - One; 3 - (2 - (4 - or - toluilpiperazin - 1 - il) ethyl) quinazolin-4 (3H) - One; 2 - ethyl - 3 - (2 - (4 - (trifluoromethyl) phenyl) piperazin-1-yl) ethyl) quinazolin-4 (3H) - One; among others. It also relates to a Pharmaceutical composition.These compounds are modulators of serotonergic receptor 5-ht1a and 5-ht2a being useful in the treatment of depression, anxiety, phobias, obsessive compulsive disorder, Addictions,