Novel derivatives of 1-((4,5-dihydro-1H-imidazol-2-yl) methyl)-1H-indazole and 1-((4,5-ihydro-1H-imidazol-2-yl) methyl)-1H-indole and method of preparation thereof

摘要

the subject of the invention are new derivatives of 1 - ((4,5 - dihydro - 1h imidazole - 2 - yl) methyl) - 1h - indazolu and 1 - ((4,5 - dihydro - 1h imidazole - 2 - yl) methyl) - 1h indole of general formula 1 in which r1, r2, r3,r4 represent hydrogen atom, alkyl, halogen, r5 means alkoksyl, hydrogen atom, alkyl, preferably methyl, halogen atom alkoksyl, preferably chlorine, the letter m means the number of 0, 1, or 2,and hx is sulfuric acid, phosphoric acid, acetic acid, oxalic, malonic, fumarowy, lactic, tartaric, citric acid, gluconic acid, p - toluenosulfonowy, methanesulphonate, hydrogen bromide or hydrogen iodide.especially hydrogen chloride.the subject of the invention is also a method for obtaining new derivatives of formula 1.wykazujacych antagonistic effects influence on receptors? 1 - adrenergic and applicable to production of medicine to treat cardiovascular circulation, especially nadcisnienia ductus arteriosus.nadcisnienia plucnego and peripheral arterial spasm, lagodnego hypertrophy gruczolu hyperplasia, or the means dzialajacych organoochronnie.