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Myricetin-caffeine co-crystal and a method for preparing mricetin-caffeine co-crystal

机译:杨桃素-咖啡因共晶及其制备方法

摘要

the invention relates to kokrysztalu mirycetyna - caffeine model 3, which applies in a pharmaceutical and / or cosmetics.the invention discloses also a way receive kokrysztalu mirycetyna - caffeine model 3 charakteryzujacy it, with mirycetyne in amounts of from 25 to 50 mg, and caffeine in amounts of from 15 to 30.5 mg is mixed with 5 to 10 ml of methanol or ethanol (99.8%), after which the whole przesacza, then leaves at room temperature by slow evaporation.and after 1 to 2 days they harvest krysztaly.in another variation of receiving kokrysztalu mirycetyna - caffeine model 3 in a steel vessel mlyna ball have to mira cetyne and caffeine in quantities of 1: 1, the stoichiometricthen the following are polar, aprotyczny solvent in amounts of 50? l for every 50 mg mirycetyny, then mieszanine being milled by time from 5 to 45 minutes, with czestosci drgan 50 - 60 hzand so obtained microcrystalline material drought in room temperature by time from 12 to 24 hours and subjected to analysis dyfraktometrze proszkowym.
机译:本发明涉及可用于药物和/或化妆品中的kokrysztalu mirycetyna-咖啡因模型3。本发明还公开了一种接受kokrysztalu mirycetyna-咖啡因模型3 charakteryzujacy的方法,其中mirycetyne的量为25至50mg,和将15至30.5 mg的咖啡因与5至10 ml的甲醇或乙醇(99.8%)混合,然后将整个przesacza,然后在室温下通过缓慢蒸发而离开.1-2天后,它们收获krysztaly。在接收kokrysztalu mirycetyna-咖啡因模型3的另一个变体中,钢制的mlyna球中met cetyne和caffeine的量为1:1,化学计量的以下是极性的,无溶剂的溶剂,量为50?每50 mg米替西定l,然后将米赞宁在5至45分钟的时间内碾磨,并用czestosci drgan 50-60 hz碾磨,因此在室温下12至24小时的时间获得微晶材料干旱,并对其进行分析。

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