compound co-crystal, method for preparing a compound co-crystal, pharmaceutical composition, use of a compound co-crystal, and method for treating arterial thrombotic complications

摘要

co-crystal of the compound, method for preparing a co-crystal of the compound, pharmaceutical composition, use of a co-crystal of the compound, and method of treating arterial thrombotic complications. The present invention relates to novel co-crystal forms of the compound of formula (I); wherein the co-forming molecule is selected from glycolic acid, salicylic acid, decanoic acid (capric), gentisic acid (2,5-dihydroxy benzoic acid), glutaric acid, vanillic acid (4-hydroxy-3 acid). -methoxy benzoic), succinic acid, malonic acid or maltol (3-hydroxy-2-methyl-4-pyrone); and processes for their preparation, pharmaceutical compositions containing such co-crystals, and the use of such co-crystals in the manufacture of medicaments for use in the prevention of arterial thrombotic complications in patients with coronary, cerebrovascular or peripheral vascular artery disease. and methods for treating such diseases in the human or animal body by administering a therapeutically effective amount of a co-crystal of the compound of formula (I).