azd maleate co-crystal 1152, crystalline form, method of preparation of azd maleate co-crystal 1152, pharmaceutical composition, and use of azd maleate co-crystal 1152

摘要

"AZD 1152 MALEATE CO-CRYSTAL, CRYSTALLINE FORM, AZD 1152 MALEATE CO-CRYSTAL METHOD, PHARMACEUTICAL COMPOSITION, AND USE OF A AZD 1152 MALEATE CO-CRYSTAL". The present invention relates to a new 2- {ethyl [3 - ({4 - [(5- {2- (3-fluorophenyl) amino] -2-oxoethyl} -1H-pyrazole dihydrogen phosphate co-crystal -3-yl) amino] quinazolin-7-yl} oxy) propyl} amino} ethyl (AZD 152) which is an aurora kinase inhibitor, which is useful in the treatment of hyperproliferative diseases, such as cancer.