The procedure for the establishment of a differentiated urothelium on naked human amniotic membrane

摘要

the object of the invention, which belongs to the field of tissue engineering, the procedure for the establishment of a differentiated urotelija (3) on the naked human amniotic membrane (4) as tkivnem medium and with a construct and amniotic membrane (4) and with a high degree of differentiation urotelija (3).the procedure for the establishment of a differentiated urotelija (3) used as the naked human amniotic membrane tissue (4). the unique structure of the basal lamine (9) and growth factors that are released izproteoglikanov (12) and amniotic membrane (4) represents a tissue carrier for attachment, proliferation and differentiation urotelijskih cells.urotelijske cells on amniotic membrane (4) in the form veu010dskladen urotelij (3) consisting of a basal (8), intermediate (7) and the surface (6) urotelijskih highly differentiated cells. highly differentiated urotelij (3) raised on naked amniotic membrane (4) urotelija successfully mimics the in vivo. this represents a unique model for basic studies such as tudiaplikativne lower urinary tract.a model for preclinical testing of various components, as well as the development of potential new drugs.