New ABCB1 polymorphisms associated with a lack of clinical response to drugs

摘要

Procedure for determining the prognosis of a clinical response of a human patient to a medicamentoactivo on the central nervous system (CNS), which is a substrate for ABCB1 protein, wherein lapresencia at least one polymorphism is determined in the ABCB1 gene that patient that is associated with a backward partial suboptimal or absent respuestaclínica to said medicament, and wherein determining at least one rs4148740 primerpolimorfismo.