首页> 外国专利> Chimera multicomponent for use as against infection by Leishmania spp vaccine. in mammals.

Chimera multicomponent for use as against infection by Leishmania spp vaccine. in mammals.

机译：用于抵抗利什曼原虫属spp疫苗感染的嵌合体多组分。在哺乳动物中。

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摘要

The present invention relates to a multicomponent chimera HISA70 comprising 6 genes from Leishmania infantum: H2A, H2B, H3, H4, A2 and HSP70. Also, it relates to an immunogenic composition comprising said multicomponent chimera and the use of said composition in the preparation of a vaccine against Leishmania spp., To confer protection against leishmaniasis, including cutaneous leishmaniasis, and visceral leishmaniasis, to mammals.

机译：本发明涉及一种多组分嵌合体HISA70，其包含来自婴儿利什曼原虫的6个基因：H2A，H2B，H3，H4，A2和HSP70。本发明还涉及包含所述多组分嵌合体的免疫原性组合物，以及所述组合物在制备针对利什曼原虫的疫苗中的用途，以赋予哺乳动物以针对包括皮肤利什曼病和内脏利什曼病在内的利什曼病的保护作用。

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公开/公告号ES2415516A2

专利类型
公开/公告日2013-07-25

原文格式PDF
申请/专利权人 UNIVERSIDAD COMPLUTENSE DE MADRID;
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申请/专利号ES20110001355
发明设计人 ORDEN GUTIERREZ JOSE ANTONIO;FUENTE LOPEZ RICARDO DE LA;CARRION HERRERO FCO. JAVIER;DOMINGUEZ BERNAL GUSTAVO;
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申请日2011-12-23
分类号C07K19/00;A61K39/008;C12N15/30;
国家 ES
入库时间 2022-08-21 16:38:36

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