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Method for predicting a risk of adverse drug reactions by determining HLA-B 1502

机译:通过确定HLA-B 1502预测药物不良反应风险的方法

摘要

A method of assessing in a human patient, the risk of developing an adverse reaction to unmedicamento in response to a drug, comprising detecting the presence of HLA-B * 1502 in a sample obtained from the patient and correlating the presence of HLA-B * 1502 in the sample with increased risk of developing a reacciónadversa a drug in the patient in response to the drug, wherein the adverse reaction to a medicamentoes the Stevens-Johnson syndrome or toxic epidermal necrolysis and the drug is oxcarbazepine or licarbazepine.
机译:一种在人类患者中评估对药物产生非药物反应不良反应的风险的方法,包括检测从患者获得的样品中HLA-B * 1502的存在并将HLA-B *的存在相关样品中的1502具有增加的对患者产生对药物的反应的风险,其中对药物的不良反应是史蒂文斯-约翰逊综合症或中毒性表皮坏死,药物为奥卡西平或利卡西平。

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