IGF-1 AS FELINE VACCINE ADJUVANT, IN PARTICULAR AGAINST FELINE RETROVIRUSES

摘要

The invention relates to feline IGF-1, to the nucleotide sequence encodingthis protein and to the use of IGF-1 as adjuvant for the vaccination of cats,in particular against the feline retroviruses FIV and FeLV. IGF-1 may be usedin the form of protein or may be expressed in vivo by a suitable, e.g. viralor plasmid, expression vector. The invention relates to all types of vaccines,namely inactivated, attenuated, sub-unit and recombinant vaccines. The vectorsexpressing IGF-1 in vivo may also be used in immunity-stimulating compositions.