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CHIMERIC AND HUMANIZED ANTIBODIES TO .ALPHA.5.BETA.1 INTEGRIN THAT MODULATE ANGIOGENESIS
CHIMERIC AND HUMANIZED ANTIBODIES TO .ALPHA.5.BETA.1 INTEGRIN THAT MODULATE ANGIOGENESIS
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机译:嵌合和人工抗体对.ALPHA.5.BETA.1整合素的调节血管生成。
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摘要
The present invention provides chimeric and humanized antibodies that specifically recognize .alpha.5.beta.1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.
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