ALKYLAMINE AS AN ANTIMICROBIAL AGENT IN OPHTHALMIC COMPOSITIONS

摘要

A multi-purpose contact lens care solution having high activity against fungiand certain bacteria comprising, in liquid aqueous medium, an alkylaminehaving the following Formula (I) , R1 R2 I R3 where R1 is a C13-17 alkylamine,and R2 and R3 are each independently H or -CH3, and a non-ionic surfactant.The solution may optionally also include additional antimicrobial components,a buffer component, a viscosity inducing component, a surfactant, taurine,propylene glycol and/or a tonicity component. This solution additionallyprevents losses in ocular tissue membrane integrity during contact lens wear.