A NOVEL BLOOD SUBSTITUTE WITH COMPLETE RED BLOOD CELL FUNCTIONS

摘要

The present document describes a soluble complex which comprises ahemoglobin cross-linked with an antioxidant enzyme, and acid-base and carbondioxide transport enzyme. Cross-linking is enhancing in vivo circulation timeofthe soluble complex, and prevents harmful in vivo effects that could besustainedby an individual subjected to the individual free components of the solublecomplex.