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A COMPUTER-IMPLEMENTED SYSTEM AND METHOD FOR THE PREDICTION OF CANCER RESPONSE TO GENOTOXIC CHEMOTHERAPY AND PERSONALISED NEOADJUVANT TREATMENTS (PCCP)
A COMPUTER-IMPLEMENTED SYSTEM AND METHOD FOR THE PREDICTION OF CANCER RESPONSE TO GENOTOXIC CHEMOTHERAPY AND PERSONALISED NEOADJUVANT TREATMENTS (PCCP)
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机译:预测癌症对基因氧化疗法和个性化新辅助治疗(PCCP)的反应的计算机实现的系统和方法
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摘要
A method for predicting an individual's response to a treatment for cancer, the method comprising a step of assaying a biological sample from the individual to determine the abundance of a panel of two or more biomarkers comprising pro-apoptotic and/or anti- apoptotic biomarkers; inputting the abundance value for the two biomarkers into a computational model of a mitochondrial apoptosis pathway; and processing said abundance values using said computational model to provide a value to predict the individual's response to treatment.
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