TRANSGENIC MICE CONTAINING CLCN4 CHLORIDE ION CHANNEL GENE DISRUPTIONS
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机译:含有CLCN4氯化物离子通道基因突变的转基因小鼠
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摘要
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a CLCN4 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
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