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Recombinant measles viruses expressing epitopes of antigens of RNA viruses and use of the recombinant viruses for the preparation of vaccine compositions

机译:表达RNA病毒抗原表位的重组麻疹病毒和重组病毒在制备疫苗组合物中的用途

摘要

The invention relates to a recombinant measles virus expressing a heterologous amino acid sequence derived from an antigen of a determined RNA virus, said recombinant measles virus being capable of eliciting a humoral and/or a cellular immune response against measles virus or against said RNA virus or against both measles virus and against said RNA virus. ??It also relates to the use of said recombinant measles virus for the preparation of immunogenic composition.
机译:本发明涉及表达源自确定的RNA病毒的抗原的异源氨基酸序列的重组麻疹病毒,所述重组麻疹病毒能够引起针对麻疹病毒或针对所述RNA病毒的体液和/或细胞免疫应答。既可以抵抗麻疹病毒,又可以抵抗所述RNA病毒。它还涉及所述重组麻疹病毒在制备免疫原性组合物中的用途。

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