GENETICALLY MODIFIED CYCLIC-NUCLEOTIDE CONTROLLED ION CHANNELS AND THE USE THEREOF

摘要

The invention relates to genetically modified cyclic-nucleotide controlled ion channels, where the sub-units thereof are altered in such a manner that they exhibit a higher sensitivity for cAMP and/or a higher selectivity for cAMP in relation to cGMP in comparison with the Wildtype according to SEQ ID NO 1 and 2.