MAGNETIC BEAD AGGREGATION ASSAY SYSTEM AND METHOD FOR ANALYSING AND CHARACTERISING MAGNETIC BEAD AGGREGATION AND DETECTION OF TARGET ANALYTES

摘要

There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: - providing magnetic beads comprising a capture probe for binding with said target analyte; - reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterisation of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterising the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.