METHOD FOR OBTAINING HYDROXYTYROSOL EXTRACT, MIXTURE OF HYDROXYTYROSOL AND 3,4-DIHYDROXYPHENYLGLYCOL EXTRACT, AND HYDROXYTYROSYL ACETATE EXTRACT, FROM BY-PRODUCTS OF THE OLIVE TREE, AND THE PURIFICATION THEREOF

摘要

The invention relates to a method for obtaining an extract comprising hydroxytyrosol, as an acetylated product or as a mixture with 3,4 dihydroxyphenylglycol and the purification thereof, comprising at least one column chromatography of a hydroxytyrosol source such as by-products of the olive and the olive tree, using a mixture of at least two ionic resins, preferably an anionic resin with a cationic resin. Preferably, in a first phase, a phenol-rich liquid is obtained as the raw material for the extraction and purification of phenolic compounds, a second phase enables a hydroxytyrosol (HT)-enriched extract and a hydroxytyrosol with 3-4-dihydroxyphenylglycol (DHFG) mixture to be obtained, and hydroxytyrosyl acetate is produced, and, in the third phase, highly pure hydroxytyrosol, DHFG, the mixture thereof and HT acetate are obtained. Each phase comprises extraction, reaction, concentration, adsorption and desorption, using mixtures of ion exchange resins, adsorption in non-ionic resins and a polymer phenolic fraction, membranes of reverse osmosis and evaporators.