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Intralymphatic immunization for inducing sustained effector CTL responses
Intralymphatic immunization for inducing sustained effector CTL responses
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机译:淋巴内免疫以诱导持续的效应子CTL反应
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摘要
A method of inducing a cytotoxic T-lymphocyte (CTL) response to an antigen is disclosed. The method involves delivering the antigen to the lymphatic system of an animal regularly over a sustained period of time using, e.g., an osmotic pump. The method is advantageous over prior art methods for inducing a CTL response in that it does not require repetitive immunizations or the use of adjuvants. The method of the present invention can be used for the induction of CTLs in tumor or infectious disease immunotherapy.
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