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METHOD AND APPARATUS FOR HIGH RESOLUTION SPATIALLY MODULATED FLUORSCENCE IMAGING AND TOMOGRAPHY
METHOD AND APPARATUS FOR HIGH RESOLUTION SPATIALLY MODULATED FLUORSCENCE IMAGING AND TOMOGRAPHY
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机译:高分辨率空间调制荧光成像和层析成像的方法和装置
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摘要
An improvement in a method for quantitative modulated imaging to perform depth sectioned reflectance or transmission imaging in a turbid medium, such as human or animal tissue is directed to the steps of encoding periodic pattern of illumination preferably with a fluorescent excitation wavelength when exposing a turbid medium to the periodic pattern to provide depth-resolved discrimination of structures within the turbid medium; and reconstructing a non-contact three dimensional image of the structure within a turbid medium. As a result, wide field imaging, separation of the average background optical properties from the heterogeneity components from a single image, separation of superficial features from deep features based on selection of spatial frequency of illumination, or qualitative and quantitative structure, function and composition information is extracted from spatially encoded data.
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