A tablet composition for a controlled and pH-independent release of the pharmaceutically active compound pramipexole from the tablet matrix after oral administration has been provided. The composition comprises a] an active granulate comprising a water-soluble, preferably dihydrochloride, salt of pramipexole, at least one non-ionic, not gelling release-controlling polymer and, optionally, a water-insoluble filler/binder and b] a tablet matrix, in which the active granulate is uniformly dispersed, said matrix comprising at least one non-ionic gelling release-controlling polymer.
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