首页> 外国专利> ALKALINE PHOSPHATASE FOR INCREASING THE ACTIVITY OF THE IMMUNE SYSTEM OF A MAMMAL AT RISK OF INFLAMMATORY DISEASES

ALKALINE PHOSPHATASE FOR INCREASING THE ACTIVITY OF THE IMMUNE SYSTEM OF A MAMMAL AT RISK OF INFLAMMATORY DISEASES

机译:碱性磷酸酶可提高感染性疾病风险的哺乳动物免疫系统的活性

摘要

The present invention relates to methods for increasing the activity of the immune system and, especially, to methods for increasing the activity of the immune system by modulation of endogenous ectophosphatase levels. According to a particularly preferred embodiment, the present invention relates to methods for the prophylaxis of mammals, and especially human mammals, at risk of inflammatory diseases such as mammals suffering from conditions such as surgery, digestive tract diseases, respiratory diseases, skin diseases, burn wounds, smoke inhalation, intoxication, severe blood loss, food poisoning, chemotherapy, radiation therapy, severe trauma or liver diseases, immunocompromised conditions. For this, the present invention provides Use of an ectophosphatase for the preparation of a medicament for the prophylaxis of a mammal at risk of inflammatory diseases.
机译:本发明涉及增加免疫系统活性的方法,尤其涉及通过调节内源性外切磷酸酶水平来增加免疫系统活性的方法。根据一个特别优选的实施方案,本发明涉及预防具有炎症性疾病风险的哺乳动物,尤其是人类哺乳动物的方法,例如患有诸如外科手术,消化道疾病,呼吸系统疾病,皮肤疾病,烧伤等病症的哺乳动物。伤口,吸入烟雾,中毒,严重失血,食物中毒,化学疗法,放射疗法,严重创伤或肝脏疾病,免疫功能低下的状况。为此,本发明提供了胞外磷酸酶在制备用于预防处于炎性疾病风险中的哺乳动物的药物中的用途。

著录项

  • 公开/公告号EP2252324B1

    专利类型

  • 公开/公告日2013-04-17

    原文格式PDF

  • 申请/专利权人 ALLOKSYS LIFE SCIENCE B V;

    申请/专利号EP20090715588

  • 发明设计人 BRANDS RUDI;

    申请日2009-02-27

  • 分类号A61K38/46;A61P29/00;A61P37/04;A61P41/00;A61P1/00;A61P11/00;A61P17/00;A61P9/00;A61P1/16;A61P39/00;

  • 国家 EP

  • 入库时间 2022-08-21 16:33:59

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