Conjugates of perphenazine or fluphenazine with carboxylic acids

摘要

A chemical conjugate comprises a first chemical moiety covalently linked to a second chemical moiety, wherein said first chemical moiety is a residue of an anti-psychotic drug residue and further wherein said second chemical moiety is a residue of an organic acid residue having 3-5 carbon atoms, said organic acid residue is selected so as to reduce side effects induced by said anti-psychotic drug when said anti-psychotic drug is administered per se and/or to exert antiproliferative activity.