首页> 外国专利> NOVEL COMPOUND WITH SPIRO CHIRAL CARBON BACKBONE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

NOVEL COMPOUND WITH SPIRO CHIRAL CARBON BACKBONE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

机译:带有螺旋手性碳骨架的新型化合物,其制备方法以及包含该化合物的药物组合物

摘要

Provided are a novel compound with a spiro chiral carbon backbone, a stereoisomer thereof, an enantiomer thereof, an in vivo hydrolysable precursor thereof, or a pharmaceutically acceptable salt thereof. The novel compound with the spiro chiral carbon backbone has excellent osteoblast differentiation activity, mast cell inhibitoryactivity, and fatty acid synthesis inhibitory activity in the liver. Therefore, the novel compound can be expected to play an innovative role in treatment of osteoporosis, fatty liver, and obesity.
机译:提供了具有螺手性碳骨架的新型化合物,其立体异构体,其对映异构体,其体内可水解前体或其药学上可接受的盐。具有螺旋手性碳骨架的新型化合物在肝脏中具有优异的成骨细胞分化活性,肥大细胞抑制活性和脂肪酸合成抑制活性。因此,可以期望该新型化合物在骨质疏松症,脂肪肝和肥胖症的治疗中发挥创新作用。

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