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MUTANT LOW-DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN WITH INCREASED BINDING TO ALZHEIMER AMYLOID-BETA PEPTIDE
MUTANT LOW-DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN WITH INCREASED BINDING TO ALZHEIMER AMYLOID-BETA PEPTIDE
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机译:突变型低密度脂蛋白受体相关蛋白,与阿尔谢迈淀粉淀粉多肽的结合增加
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摘要
A mutant low-density lipoprotein receptor related protein-1 binds to Alzheimer amyloid-beta (A) peptide with greater affinity compared to its wild-type homolog. This binding may be used to detect A or to separate A from the rest of a subject's body. In Alzheimer disease, it may be used to provide diagnostic results by detecting A, treatment by removing A, or both.
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