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Methods for treatment and prevention of tauopathies and amyloid beta amyloidosis by modulating CRF receptor signaling
Methods for treatment and prevention of tauopathies and amyloid beta amyloidosis by modulating CRF receptor signaling
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机译:通过调节CRF受体信号转导来治疗和预防tauopathies和淀粉样β淀粉样变性病的方法
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摘要
Methods for treating or preventing tauopathies and/or Aβ amyloidosis by modulating CRF receptor signaling. Accumulation of hyperphosphorylated tau protein in the CNS may be reduced by administration of CRF-R1 selective antagonists and/or CRF-R2 selective agonists. For example, in some aspects, methods for preventing the onset of Alzheimer's disease by administration of CRF-R1 selective antagonists are provided.
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