首页> 外国专利> METHODS FOR QUANTITATIVE CHIRAL DETERMINATION OF THE d- AND l- ENANTIOMERS OF AMPHETAMINE AND METHAMPHETAMINE

METHODS FOR QUANTITATIVE CHIRAL DETERMINATION OF THE d- AND l- ENANTIOMERS OF AMPHETAMINE AND METHAMPHETAMINE

机译：盐酸安非他明和甲基苯丙胺 d -和 I -对映体的定量手性测定方法

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摘要

Methods for the chiral separation and quantitative determination of the d- and l- enantiomers for amphetamine and methamphetamine in bodily fluids and tissues are provided. The method comprises providing a bodily fluid or tissue sample from a subject, extracting target analyte(s) from the sample, followed by eluting on a liquid chromatography column comprising a chiral stationary phase to yield an eluent, which is then analyzed for the presence of the analytes using a mass analyzer. 展开▼

机译：提供了用于体液和组织中苯丙胺和甲基苯丙胺的 d -和 I -对映体的手性分离和定量测定的方法。该方法包括提供来自受试者的体液或组织样品，从样品中提取目标分析物，然后在包含手性固定相的液相色谱柱上洗脱以产生洗脱液，然后分析洗脱液的存在。使用质量分析仪分析被分析物。 展开▼

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公开/公告号WO2013103841A1

专利类型

公开/公告日2013-07-11

原文格式PDF

申请/专利权人 CLINICAL REFERENCE LABORATORY INC.;
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申请/专利号WO2013US20316

发明设计人 KUNTZ DAVID J.;HERRERA MICHAEL J.;
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申请日2013-01-04

分类号G01N30/72;G01N30/02;G01N33/483;

国家 WO

入库时间 2022-08-21 16:31:56

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