USE OF TRANSFORMING GROWTH FACTOR - BETA 1 (TGF- 1) INHIBITOR PEPTIDES FOR THE TREATMENT OF CORNEAL FIBROSIS AND/OR HAZE

摘要

The described peptides possess the capacity to bind to Transforming Growth Factor TGF-1 (TGF-1), and are potential inhibitors of the biological activity of TGF-1 through direct binding to this cytokine. These peptides can be used in the treatment of diseases or pathological alterations based on excessive or deregulated TGF-1 expression, e.g., liver fibrosis, pulmonary fibrosis, corneal fibrosis and haze.