ORAL PREPARATION FOR PROMOTING EXPRESSION OF TGF-β, ORAL PREPARATION FOR INHIBITING PRODUCTION OF PAIN-MEDIATING SUBSTANCE, AND ORAL PREPARATION FOR PREVENTING EDEMA

摘要

An oral preparation for promoting the expression of TGF-β comprises hyaluronic acid or a pharmaceutically acceptable salt thereof as an active ingredient, and can promote the expression of TGF-β in plasma. An oral preparation for inhibiting the production of a pain-mediating substance comprises hyaluronic acid or a pharmaceutically acceptable salt thereof as an active ingredient, and can promote the expression of TGF-β in plasma to thereby inhibit the production of the pain-mediating substance. An oral preparation for inhibiting the production of a pain-mediating substance comprises hyaluronic acid or a pharmaceutically acceptable salt thereof as an active ingredient, and can inhibit the production of PGE2 and/or bradykinin which is a pain-mediating substance. An oral preparation for preventing edema comprises hyaluronic acid or a pharmaceutically acceptable salt thereof as an active ingredient, and can inhibit the production of PGE2 and/or bradykinin which is a pain-mediating substance.