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Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels

机译:保护神经元组织免受谷氨酸水平升高所致损伤的方法和组合物

摘要

The present invention concerns a glutamate modifying transaminase for use in the treatment of a medical condition selected from the group consisting of brain anoxia, brain ischemia, stroke, perinatal brain damage, traumatic brain injury, bacterial meningitis, subarachnoid haemorhage, migraine, stress, hemorrhagic shock, epilepsy, acute liver failure, glaucoma, HIV, dementia, amyotrophic lateral sclerosis (ALS), spastic conditions, open heart surgery, aneurism surgery, coronary artery bypass grafting and Alzheimer's disease.
机译:本发明涉及用于治疗选自脑缺氧,脑缺血,中风,围生期脑损伤,外伤性脑损伤,细菌性脑膜炎,蛛网膜下腔出血,偏头痛,压力,出血性疾病的医学病状的谷氨酸修饰转氨酶。休克,癫痫,急性肝功能衰竭,青光眼,HIV,痴呆,肌萎缩性侧索硬化(ALS),痉挛性疾病,开放性心脏手术,动脉瘤手术,冠状动脉搭桥术和阿尔茨海默氏病。

著录项

  • 公开/公告号EP2561889A3

    专利类型

  • 公开/公告日2013-04-03

    原文格式PDF

  • 申请/专利权人 YEDA RESEARCH AND DEVELOPMENT CO. LTD.;

    申请/专利号EP20120160145

  • 发明设计人 TEICHBERG VIVIAN;

    申请日2003-07-31

  • 分类号A61K38/43;A61K38/44;A61K38/45;A61K31/19;A61K38/51;A61K38/52;

  • 国家 EP

  • 入库时间 2022-08-21 16:30:40

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