PENTAPEPTIDE DERIVATIVES FOR PROMOTING HAIR GROWTH

摘要

The invention relates to substituted pentapeptide compounds of the formula R1-Gly-Pro-Ile-Gly-A1 (I), where A1 is Ser or Thr and R1 denotes -C(=O)-H, -C(=O)-C1-C24 alkyl, -C(=O)-CH2CH(OH)CH2N+(CH3)3 (carnitinoyl), 1,2-Dithiolane-3-pentanoyl (liponoyl), -C(=O)-(CH2)2NHC(=O)CH(OH)C(CH3)2CH2OH (pantothenoyl) or (II) (biotinyl) in free form or in salt form, to the use thereof to produce cosmetic dermatologically active compositions, to said compositions, to the use thereof as hair growth promoters, and to a cosmetic method for promoting hair growth.