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In vitro method for predicting whether a compound is genotoxic in vivo.
In vitro method for predicting whether a compound is genotoxic in vivo.
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机译:体外预测化合物在体内是否具有遗传毒性的方法。
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摘要
The invention is in the field of genomics and it provides an in vitro method for predicting whether a compound is genotoxic in vivo. It provides a method that employs the analysis of expression profiles of microRNAs in cells exposed to a potentially genotoxic compound. It was found that differential expression of a number of microRNAs could reliably predict whether a compound was a genotoxic or a non-genotoxic compound.
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