SUSTAINED-RELEASE FORMULATION CONTAINING PREGABALIN AND ONE OR MORE SELECTED AMONG A SWELLING AGENT, A MATRIX FORMING AGENT, AND A VAPOR GENERATING AGENT

摘要

PURPOSE: A sustained-release formulation containing pregabalin is provided to stably and continuously release pregabalin and to ensure an anti-seizure property.;CONSTITUTION: A sustained-release formulation contains pregabalin and one or more selected among a swelling agent, a matrix forming agent, and a vapor generating agent. The matrix forming agent is hypromellose. The viscosity of the matrix forming agent is 4000-150000 cps. The swelling agent is sodium starch glycolate. The vapor generating agent is sodium bicarbonate.;COPYRIGHT KIPO 2013;[Reference numerals] (AA) Embodiment 1; (BB) Comparative embodiment 2; (CC) Comparative embodiment 3