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MICROARRAY AND KIT FOR DIAGNOSING LANGER-GIEDION SYNDROME
MICROARRAY AND KIT FOR DIAGNOSING LANGER-GIEDION SYNDROME
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机译:微阵列和工具箱诊断血管扩张综合征
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摘要
PURPOSE: A microarray and a kit for diagnosing Langer-Giedion syndrome are provided to identify an accurate amplification of a gene by dyeing two samples with different fluorescent substances and expressing the ratio value of the dyeing difference between the two samples numerically, thereby shortening the diagnosis time. CONSTITUTION: A microarray for diagnosing Langer-Giedion syndrome contains genome DNA fragments of one or more kinds, 20-100bp oligonucleotide, 100bp-10kbp cDNA, and probes of one or more kinds. The 20-100bp oligonucleotide is subsequently arranged inside the genome DNA fragments. The cDNA is derived from the genome DNA fragments. The probes are selected from a group consisting of the complements of the genome DNA fragments, oligonucleotide, and cDNA. For the probes, the maximum rate of containing repetitive sequence in the base sequence is 85%. The base sequence comprising the probes has a feature of single locus in chromosomes.
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