ANTIBACTERIAL DENTAL MEMBRANE WHICH ENHANCES ALKALINE PHOSPHATASE ACTIVITY IN OSTEOBLAST

摘要

PURPOSE: An antibacterial dental membrane is provided to ensure alkaline phosphatase activity in osteoblast, and to improve bond generation in a lesion.;CONSTITUTION: A dental membrane contains 0.01-10 wt% of 4-hexylresorcinol, and 90-99.99 wt% of silk proteins. The silk protein is silk fibroin. A method for manufacturing the dental membrane comprises: a step of dissolving the silk fibroin in an ethanol solution containing a salt, and removing the salt and ethanol to prepare a silk fibroin solution; a step of dissolving 4-hexylresorcinol in ethanol and preparing 4-hexylresorcinol ethanol solution; a step of mixing the silk fibroin solution and the 4-hexylresorcinol ethanol solution, and comprising a dental membrane composition; and a step of pouring the dental membrane composition into a container and drying.;COPYRIGHT KIPO 2013;[Reference numerals] (AA) Control group without applying a membrane; (BB) Experimental group with applying the membrane of the present invention composed of 3% hexylresorcinol and remaining amount of silk fibroin(an arrow indicates a remaining dental membrane);